2/ a[mfrkef; aomufaq;rsm; (Oral Hormonel Contraceptives)
aygif;pnf; a[mfrkef;aomufaq;rsm;
(Combined Oral Contraceptive Pills- COCs)
y#doaE¨wm; a[mfrkef;aomufaq;awG t*FvefEdkifiHtwGif; toHk;NyKcGifhukd 1961 ckESpfrSm xkwfay;cJhygw,f/ tufpfx&dk*sif (Estrogen) eJU y&dk*sufpfx&dk*sif (Progestrogen) vdkUac:wJh ]r} a[mfrkef; 2 rsdK; yg0ifygw,f/ a[mfrkef; 2 rsdK;udk aq;wpfrsdK;xJrSm aygif;NyD; toHk;NyKNcif;aMumifh wrsdK;pD&JU vkdtyfwJh aq;yrmP ododomom avsmhcsvdkU &NyD; ab;xGuf qdk;usdK; (Side Effects) rsm; tNzpfenf;vmapygw,f/ aps;uGufay: pwif a&muf&Sdvmcsdefuae tcktcsdeftxd oHk;pGJol trsdK;orD;aygif; oef; 200 ausmf &SdvmNyDNzpfNyD; t*FvefEkdifiHwGif; oHk;pGJolOD;a& 3 oef;txd &Sdygw,f/ COC aq;rsm;[m toHk;NyK&wmvnf; vG,fulNyD; pdwfcs&wJh tNyif tNcm;aumif;usdK;rsm;vnf; &Ekdifygao;w,f/ t"duoHk;pGJolawGuawmh i,f&G,fNyD; usef;rma&;aumif;wJh trsdK;orD;awG Nzpfygw,f/
aq;yg0ifrIrsm; (Formulations)
aps;uGufrSm aq;wHqdyf trsdK;rsdK;&SdEkdifNyD; aq;yg0ifrI &mcdkifEIef;rsm;vnf; trsdK;rsdK; &Sdwwfygw,f/ trsm;pkuawmh Ethinyl oestradiol vdkUac:wJh tufpfx&kd*sif udk waeUrSm 20 rS 35 rDvD*&rf txdygatmif pDrHxm;ygw,f/ tufpfx&kd*sif yrmPudk 'Dhxufavsmhr,fqkd&if &moDudk xdef;csKyfrI raumif; (&moD rrSefrI) Nzpfwwfygw,f/ tufpfx&dk*sif yrmPrsm;rsm; aq;rsm; (50 rDvD*&rf txuf) udk xl;Ncm;wJh taNctaersm;rSmom ay;avh&Sdygw,f/ tufpfx&dk*sif yrmP rsm;Ncif;[m aoG;vTwfaMumrsm;eJU aoG;NyefaMumrsm;rSm aoG;cJNcif;a&m*geJU qufEG,frI &Sdaewm awGU&vdkU Nzpfygw,f/ vwfwavm aps;uGufrSm awGUae&wJh COC aq;rsm;[m 'kwd,eJU wwd, rsdK;quf (taNccH pxkwfvdkufaom aq;xuf wNznf;Nznf; tmedoifydkaumif;vmatmif xkwfvkyfxm;aom aq;rsm;) y&dk*sufpfx&dk*sif a[mfrkef;udk toHk;rsm;ygw,f/
(aygif;pnf;rI) yHkpH wpfrsdK;wnf; (Monophasic) NzpfwJh aq;awG[m aq;tvHk;wkdif;rSm aeUpOfoHk;&r,fh yrmPwpfrsdK;xJ Nzpfatmif xkwfvkyfxm;ygw,f/ (aygif;pnf;rI) yHkpH 2 rsdK; (Biphasic) (odkU) yHkpH 3 rsdK; (Triphasic) NzpfwJh aq;awGuawmh &ufwcsdKUtwGuf yrmPwpfrsdK; NzpfapNyD; usef&ufrsm;twGuf yrmPwrsdk; Nzpfatmif pDrHxm;ygw,f/ (pm<uif; - obm0rSm wpf&ufeJU wpf&uf trsdK;orD; a[mfrkef; xGufrIeJU teD;pyfqHk; wlatmifxkwfzdkU MudK;pm;&if; 'Dvkd yHkpH 2 rsdK; 3 rsdK; aq;awG xGufvmwmyg)/ vwfwavm rSmawmh yrmP rwlatmif pDpOfxm;wm[m tusdK;uGm[rI odyfrsm;rsm; r&SdbJ oHk;pGJol trsdK;orD; twGufvnf; tcuftcJ &SdEkdifw,fvdkU ,lqygw,f/
COC wHqdyf trsm;pkrSm aq;tvHk;a& 21 vHk; ygavh&Sdygw,f/ aeUpOf w&ufwvHk; eJU 3 ywfwdwd aomuf&NyD; aq;raomufbJ 7 &ufae&ygw,f/ wcsdKUwHqdyfawGuawmh (arhwwf&ifvJ tqifaNyatmif) aq;raomuf&wJh 7 &uftwGuf tmedoifrygwJhaq;vHk; (Placebo) 7 vHk; pDpOfay;xm;ygw,f/ (pm<uif; - wcsdKUaq;wHqdyfawGrSm tmedoifvHk;0rygwJh aq;vHk; 7 vHk; tpm; oH"mwfygwJh aq;vHk;awG ygwwfygw,f/ txl;oNzifh tm[m& rNynfholrsm;wwfwJh zGHUNzdK;pJ EkdifiHawGrSm oHk;Muwmrsm;ygw,f/ wcsdKUuawmhvnf; a[mfrkef;aomufaq;oHk;olawG[m &moDqif;rI enf;oGm;wwfNyD; oH"mwfenf;vdkU &EkdifwJh aoG;tm;enf;a&m*g NzpfEIef; enf;yg;rSmNzpfvdkU oH"mwfygwJh 'Daq;vHk;av;awG rvdktyfbl;vdkU aNymMuygw,f)/
tmedoif txda&mufqHk;NzpfzdkUtwGuf a[mfrkef;aomufaq;rsm;udk aomufwJhtcgrSm tcsdefwck owfrSwfxm;NyD; aeUpOf tcsdefrSefrSef aomufEdkif&if taumif;qHk;ygyJ/
Credit : Dr. PuuKaung (NativeMyanmar)
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